Clare frequently performs and commissions solo, chamber and concerto works from living composers and is a keen advocate of contemporary music. To date, she has given 45 world premieres of works by composers including Kenneth Hesketh, Robert Saxton, Michael Berkeley, Arlene Sierra, John Woolrich, David Matthews, Edwin Roxburgh, John McCabe, and Andrzej and Roxanna Panufnik.

Her discography features 20 world premiere recordings, with more in the pipeline. In 2016, the Observer described her as "a star interpreter of contemporary music" while the Telegraph stated that she "brilliantly despatched" Mazurkas by Ad├Ęs at her recital for the Cheltenham Festival. Her recordings have been internationally acclaimed.